PH-responsive hierarchical transformation of charged lipid assemblies within polyelectrolyte gel layers with applications for controlled drug release and MR imaging contrast

Yi-Fong Huang; Wen-Hsuan Chiang; Wen-Chia Huang; Hsin-Hung Chen; Ming-Yin Shen; Sung-Chyr Lin; Chorng-Shyan Chern; Hsin-Cheng Chiu

doi:10.1039/c4tb00771a

Journal article

PH-responsive hierarchical transformation of charged lipid assemblies within polyelectrolyte gel layers with applications for controlled drug release and MR imaging contrast

Yi-Fong Huang, Wen-Hsuan Chiang, Wen-Chia Huang, Hsin-Hung Chen, Ming-Yin Shen, Sung-Chyr Lin, Chorng-Shyan Chern and Hsin-Cheng Chiu

Journal of Materials Chemistry B, Vol.2(31), pp.4988-4992

21/08/2014

DOI: https://doi.org/10.1039/c4tb00771a

Appears in keyword about Chemistry

Abstract

A cationic lipid-embedded poly(acrylic acid) (PAAc) gel layer coated on chitosan/superparamagnetic iron oxide nanoparticle (SPION) nanohybrid surfaces effectively modulates drug release and MR imaging contrast by pH-responsive morphological transformation and hierarchical alignment of the lipid assemblies. © 2014 the Partner Organisations.

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Title: PH-responsive hierarchical transformation of charged lipid assemblies within polyelectrolyte gel layers with applications for controlled drug release and MR imaging contrast
Creators - without role: Yi-Fong Huang - Department of Chemical Engineering, National Chung Hsing University
Wen-Hsuan Chiang - Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University
Wen-Chia Huang - Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University
Hsin-Hung Chen - Department of Chemical Engineering, National Chung Hsing University
Ming-Yin Shen - Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University
Sung-Chyr Lin - Department of Chemical Engineering, National Chung Hsing University
Chorng-Shyan Chern - National Taiwan University of Science and Technology
Hsin-Cheng Chiu - Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University
Identifiers: 9957769637006774
Academic Unit: Department of Biomedical Engineering and Environmental Sciences, College of Nuclear Science, National Tsing Hua University
Language: English
Resource Type: Journal article
Publication Details: Journal of Materials Chemistry B, Vol.2(31), pp.4988-4992

PH-responsive hierarchical transformation of charged lipid assemblies within polyelectrolyte gel layers with applications for controlled drug release and MR imaging contrast

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