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Palladium-catalyzed syntheses of oxygen- and nitrogen heterocycles via transmetalation of functionalized alkynyl stannanes
Journal article   Peer reviewed

Palladium-catalyzed syntheses of oxygen- and nitrogen heterocycles via transmetalation of functionalized alkynyl stannanes

M. Chandrasekharam, Shie-Tsung Chang, Kwei-Wen Liang, Wen-Tai Li and Rai-Shung Liu
Tetrahedron Letters, Vol.39(7), pp.643-646
12/02/1998

Abstract

The reaction between CpFe(CO) 2 I, hydroxy- or aminoalkynyl stannanes, and PdCl 2 (CH 3 CN) 2 (8.0 mol. %) generates a reactive iron-alkynyl intermediate that reacts in situ with RCHO/BF 3 ·Et 2 O to yield an iron oxa- or azacarbeniums quantitatively, further producing oxygen- and nitrogen heterocycles in high yields after Me 3 NO-oxidation of these carbenium salts.

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