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Photocatalyzed Aerobic Oxidation of Thiols to Disulfides Using Cu2O Polyhedra
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Photocatalyzed Aerobic Oxidation of Thiols to Disulfides Using Cu2O Polyhedra

Wan-Ting Dai, Chun-Chia Wen, Hsi-Jui Lin 和 Michael Hsuan-Yi Huang
ACS applied materials & interfaces, 卷.17(12), 頁碼.18268-18274
26/03/2025
PMID: 40079127
Web of Science ID: WOS:001444256600001

摘要

Materials Science, Multidisciplinary Nanoscience & Nanotechnology Science & Technology Science & Technology - Other Topics Materials Science Technology
To further demonstrate semiconductor facet effect to photocatalytic organic transformations and address a lack of using simple polyhedral semiconductor particles for disulfide bond formation, Cu2O cubes, octahedra, and rhombic dodecahedra were used to photocatalyze aerobic oxidation of 4-methylbenzenethiol. After reaction condition optimization, Cu2O crystals and N,N,N ',N '-tetramethylethylenediamine (TMEDA) were added to 4-methylbenzenethiol in ethanol for thiol oxidation to 1,2-di-p-tolyldisulfane under 390 nm light-emitting diode (LED) lamp irradiation for just 5 min. Rhombic dodecahedra gave the highest product yield, followed by octahedra, cubes, and commercial Cu2O powder. Cu2O rhombic dodecahedra were subsequently employed to photocatalyze thiols bearing a diverse scope of substituents with satisfactory yields. Reactive species trapping experiments were performed to support a plausible reaction mechanism. Semiconductor crystals with surface control can be a simple but highly effective strategy for enhancing photocatalytic organic transformations.

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dai-et-al-2025-photocatalyzed-aerobic-oxidation-of-thiols-to-disulfides-using-cu2o-polyhedra (1)2.85 MB下載檢視
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https://doi.org/10.1021/acsami.4c21206檢視
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