Photosensitization of singlet oxygen and in vivo photodynamic therapeutic effects mediated by PEGylated W18O49 nanowires

Poliraju Kalluru; Raviraj Vankayala; Chi-Shiun Chiang; Kuo Chu Hwang

doi:10.1002/anie.201307358

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Photosensitization of singlet oxygen and in vivo photodynamic therapeutic effects mediated by PEGylated W18O49 nanowires

Journal article

Peer reviewed

Photosensitization of singlet oxygen and in vivo photodynamic therapeutic effects mediated by PEGylated W18O49 nanowires

Poliraju Kalluru, Raviraj Vankayala, Chi-Shiun Chiang and Kuo Chu Hwang

Angewandte Chemie - International Edition, Vol.52(47), pp.12332-12336

18/11/2013

DOI: https://doi.org/10.1002/anie.201307358

Abstract

nanowires

photodynamic therapy

photothermal therapy

reactive oxygen species

singlet oxygen

Upon excitation with near-infrared light (980 nm), PEGylated W ₁₈ O ₄₉ nanowires can sensitize the formation of singlet oxygen and thus reactive oxygen species (ROS). The resulting photodynamic therapy (PDT) effect can cause the destruction of tumors in the absence of organic photosensitizers. PEG=poly(ethylene glycol), PTT=photothermal therapy. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Title: Photosensitization of singlet oxygen and in vivo photodynamic therapeutic effects mediated by PEGylated W18O49 nanowires
Creators - without role: Poliraju Kalluru - National Tsing Hua University
Raviraj Vankayala - National Tsing Hua University
Chi-Shiun Chiang - Department of Chemistry , Frontier Research Centre on Fundamental and Applied Sciences of Matters , National Tsing Hua University
Kuo Chu Hwang - National Tsing Hua University
Publication Details: Angewandte Chemie - International Edition, Vol.52(47), pp.12332-12336
Identifiers: 9957773489006774
Academic Unit: Institute of Analytical and Environmental Sciences, College of Nuclear Science, National Tsing Hua University; National Tsing Hua University
Language: English
Resource Type: Journal article

Photosensitization of singlet oxygen and in vivo photodynamic therapeutic effects mediated by PEGylated W18O49 nanowires

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