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Platinum- and gold-catalyzed hydrative carbocyclization of oxo diynes for one-pot synthesis of benzopyrones and bicyclic spiro ketones
Journal article   Peer reviewed

Platinum- and gold-catalyzed hydrative carbocyclization of oxo diynes for one-pot synthesis of benzopyrones and bicyclic spiro ketones

Arindam Das, Hsu-Kai Chang, Cheng-Hua Yang and Rai-Shung Liu
Organic Letters, Vol.10(18), pp.4061-4064
2008

Abstract

(Chemical Equation Presented) We report a one-pot synthesis of benzopyrones and tricyclic spiroketones from hydrative carbocyclization of oxodiyne substrates catalyzed by PtCl 2 and PPh 3 AuCl/AgOTf, respectively. The distinct carbocyclizations with R and Au catalysts stem from their altered regioselectivity in the oxo-assisted hydration of the neighboring alkyne carbons. © 2008 American Chemical Society.

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