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Remotely nano-rupturable yolk/shell capsules for magnetically-triggered drug release
Journal article   Peer reviewed

Remotely nano-rupturable yolk/shell capsules for magnetically-triggered drug release

Shang-Hsiu Hu, You-Yin Chen, Ta-Chung Liu, Tsan-Hua Tung, Dean-Mo Liu and San-Yuan Chen
Chemical Communications, Vol.47(6), pp.1776-1778
14/02/2011

Abstract

Yolk/shell capsules containing a volume/hydrophobicity transformable core and an ultra-thin silica shell have been prepared. When an external magnetic field induced the temperature, the cores exhibit a significant triggering size shrinkage and the diameter decreases more than 10 times, causing solid shells destruction and physical collapse, leading to drug burst release. © 2011 The Royal Society of Chemistry.

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