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Reversible siRNA-polymer conjugates by RAFT polymerization
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Reversible siRNA-polymer conjugates by RAFT polymerization

Karina L. Heredia, Thi H. Nguyen, Chien-Wen Chang, Volga Bulmus, Thomas P. DavisHeather D. Maynard
Chemical Communications, (28), 頁碼.3245-3247
2008
PMID: 18622432

摘要

Chemistry (all)
A straightforward synthetic method to prepare pyridyl disulfide end functionalized poly(PEG acrylate) by RAFT polymerization for efficient and reversible conjugation to siRNA is described. © The Royal Society of Chemistry.

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