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Self-Powered Forward Error-Correcting Biosensor Based on Integration of Paper-Based Microfluidics and Self-Assembled Quick Response Codes
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Self-Powered Forward Error-Correcting Biosensor Based on Integration of Paper-Based Microfluidics and Self-Assembled Quick Response Codes

Mingquan Yuan, Keng-Ku Liu, Srikanth SingamaneniShantanu Chakrabartty
IEEE Transactions on Biomedical Circuits and Systems, 卷.10(5), 頁碼.963-971
10/2016
PMID: 28113178

摘要

Flexible electronics forward error correcting biosensor ink-jet printing mobile health paper-based microfluidics self-assembly self-powered sensing silver enhancement wireless biosensor Biomedical Engineering Electrical and Electronic Engineering
This paper extends our previous work on silver-enhancement based self-assembling structures for designing reliable, self-powered biosensors with forward error correcting (FEC) capability. At the core of the proposed approach is the integration of paper-based microfluidics with quick response (QR) codes that can be optically scanned using a smart-phone. The scanned information is first decoded to obtain the location of a web-server which further processes the self-assembled QR image to determine the concentration of target analytes. The integration substrate for the proposed FEC biosensor is polyethylene and the patterning of the QR code on the substrate has been achieved using a combination of low-cost ink-jet printing and a regular ballpoint dispensing pen. A paper-based microfluidics channel has been integrated underneath the substrate for acquiring, mixing and flowing the sample to areas on the substrate where different parts of the code can self-assemble in presence of immobilized gold nanorods. In this paper we demonstrate the proof-of-concept detection using prototypes of QR encoded FEC biosensors.

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