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Shape-programmable artificial cilia for microfluidics
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Shape-programmable artificial cilia for microfluidics

Bivas Panigrahi, Vignesh SahadevanChia-Yuan Chen
iScience, 卷.24(12), 頁.103367
17/12/2021
PMID: 34825146
Web of Science ID: WOS:000740249400004

摘要

Fluidics Magnetic materials Materials in biotechnology
The artificial ciliary motion has been known not to be hydrodynamically optimal, limiting their associated applications in the microscale flow domain. One of the major hurdles of contemporary artificial cilia is its structural rigidity, which restricts their flexibility. To address this issue, this work proposed a shape-programmable artificial cilia design with distinctive polydimethylsiloxane (PDMS) and magnetic segments distributed throughout the structure, which provided precise control for time-spatial modulation of the whole artificial cilia structure under external magnetic actuation. For the fabrication of the proposed multi-segment artificial cilia, a facile microfabrication process with stepwise mold blocking followed by the PDMS and magnetic composite casting was adopted. The hydrodynamic analysis further elucidated that the proposed artificial cilia beating induced significant flow disturbance within the flow field, and the associated application was demonstrated through an efficient mixing operation. [Display omitted] •Fabrication of artificial cilia was conducted through micromilling and casting methods.•The weighted index was correlated to the bending angles of artificial cilia.•Hydrodynamic analysis of artificial cilia was performed through the μPIV analysis.•A significant improvement in mixing performance was achieved in few seconds. Fluidics; Materials in biotechnology; Magnetic materials

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https://doi.org/10.1016/j.isci.2021.103367檢視
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