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Sodium trimethylsilanethiolate in novel cyclizations for synthesis of aromatic heterotricyclic compounds
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Sodium trimethylsilanethiolate in novel cyclizations for synthesis of aromatic heterotricyclic compounds

Long-Li Lai, Pen-Yuan Lin, Wen-Hong Huang, Min-Jen Shiao 和 Jih Ru Hwu
Tetrahedron Letters, 卷.35(21), 頁碼.3545-3546
05/1994
DOI: https://doi.org/10.1016/S0040-4039(00)73233-3

摘要

Biochemistry Drug Discovery Organic Chemistry
A new method was developed for synthesis of aromatic heterotricyclic compounds in 50-64% yields from diaryls bearing a functionality including OMe, COOMe, and CN, and a leaving group (i.e., F and OMe) by use of Me 3 SiSNa in 1,3-dimethyl-2-imidazolidinone at 120-150 °C. © 1994.

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