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Synthesis of a carboxyl linker containing Pk trisaccharide
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Synthesis of a carboxyl linker containing Pk trisaccharide

S.-Y. Hsieh, M.-D. Jan, L. N. Patkar, C.-T. ChenC.-C. Lin
Carbohydrate Research, 卷.340(1), 頁.49
2005

摘要

Pk antigen;Galactosyl phosphite;Glycosylation;α-Selectivity
An efficient synthesis of a Pk trisaccharide with a functionalized side arm at the reducing end for conjugation to other molecules is presented. Construction of the Pk trisaccharide with a high α-selectivity was achieved in high yield by coupling a reactive galactosyl phosphite donor with a lactosyl acceptor.

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