摘要
Objective: To evaluate the effect of lesion length on in-stent restenosis (ISR) of vertebral artery (VA) origin stenting. Methods: We retrospectively analyzed the medical and radiological records of patients receiving VA origin stenting from March 1999 to June 2005. They were subdivided according to lesion length. ISR was defined as >50% diameter narrowing in stent. Results: Eighty symptomatic patients (64 male, mean age 72 years) with 90 lesions treated with balloon expandable tubular coronary stents were enrolled. There were 34 patients with 38 short lesions (length ≤ 5 mm, group 1), 37 patients with 42 medium lesions (length > 5 mm, <10 mm, group 2) and 9 patients with 10 long lesions (length ≥ 10 mm, group 3). Eighty seven bare-metal stents and 3 drug-eluting stents were implanted. Repeat angiography was done in 40 lesions (44%) at 11.7 ± 9.6 months. The ISR rate in group 1, 2, 3 is 21%, 29%, and 50% (p = 0.486). Multivariable Cox regression analysis showed lesion length was the only significant independent predictor of ISR (hazard ratio: 1.19, p = 0.039). Conclusion: ISR of VA origin stenting is common. Lesion length is an important predictor of ISR in VA origin stenting. © 2006 Elsevier Ltd. All rights reserved.