Logo image
返回
The first In(OTf)3-catalyzed conversion of kinetically formed homoallylic alcohols into the thermodynamically preferred regioisomers: Application to the synthesis of 22α-sterols
期刊文章   開放取用(OA)   同儕審查

The first In(OTf)3-catalyzed conversion of kinetically formed homoallylic alcohols into the thermodynamically preferred regioisomers: Application to the synthesis of 22α-sterols

Teck-Peng Loh, Kui-Thong Tan 和 Qi-Ying Hu
Angewandte Chemie - International Edition, 卷.40(15), 頁碼.2921-2922
03/08/2001
DOI: https://doi.org/10.1002/1521-3773(20010803)40:15<2921::AID-ANIE2921>3.0.CO;2-V

摘要

Ene reaction Indium Retro reactions Sigmatropic rearrangement
A retro-ene reaction that generates the parent aldehyde and a sigmatropic rearrangement are involved in the In(OTf) 3 -catalyzed conversion of homoallylic alcohols 1 into the thermodynamically favored regioisomers 2. This method can be used for the stereocontrolled synthesis of linear homoallylic 22α-sterols from their readily accessible branched 22β isomers.

檔案與連結 (1)

url
https://doi.org/10.1002/1521-3773(20010803)40:15<2921::AID-ANIE2921>3.0.CO;2-V檢視
已出版(紀錄版本) 開放

相關連結

指標

1 檢視次數

詳細資料

Logo image