Total Synthesis of (+)- and (±)-Hosieine A

Yu-Wen Huang; Ke Kong; John L. Wood

doi:10.1002/anie.201804076

Total Synthesis of (+)- and (±)-Hosieine A

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Total Synthesis of (+)- and (±)-Hosieine A

Yu-Wen Huang, Ke Kong 和 John L. Wood

Angewandte Chemie - International Edition, 卷.57(26), 頁碼.7664-7667

06/2018

DOI: https://doi.org/10.1002/anie.201804076

PMID: 29723446

摘要

electrocyclization

enantioselectivity

gold

natural products

total synthesis

Catalysis

Chemistry (all)

Described herein is a concise total synthesis of the highly potent nicotinic acetylcholine receptor ligand hosieine A in racemic and enantioenriched forms. The synthesis requires only seven steps and features a telescoped reaction sequence initiated by a gold-catalyzed Rautenstrauch reaction.

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詳細資料

題名: Total Synthesis of (+)- and (±)-Hosieine A
翻譯題名: Total Synthesis of (+)- and (±)-Hosieine A
創作者：: Yu-Wen Huang (作者) - Baylor University
Ke Kong (作者) - Baylor University
John L. Wood (作者) - Baylor University
學術資源類型: 期刊文章
出版日期: 06/2018
出版資訊: Angewandte Chemie - International Edition, 卷.57(26), 頁碼.7664-7667
語言: 英語

Total Synthesis of (+)- and (±)-Hosieine A

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詳細資料

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