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Two-Dimensional Cs2AgBiBr6-Based Biosensor for Selective and Sensitive Detection of Cardiac Biomarker Troponin I
期刊文章

Two-Dimensional Cs2AgBiBr6-Based Biosensor for Selective and Sensitive Detection of Cardiac Biomarker Troponin I

Yin-Cheng Lu, Evan Darius, Mei-Chin Lien, I-Hsiu Yeh, Hui-Fang Shi, Yung-Hsin Huang, Chien-Hung Chen, Hung-Wen Chen, Ching-Yuan Su, Ru-Yin Hsu, …
ACS Applied Nano Materials, 卷.6(24), 頁碼.23022-23028
12/2023

摘要

biosensors cardiovascular disease cTnI perovskite plasmonic nanomaterials Materials Science (all)
Inspired by graphene and transition-metal dichalcogenides (TMDs), a considerable focus has been centered on investigating and exploring two-dimensional (2D) layered materials that possess excellent electronic, optical, physical, and chemical properties. Owing to their nontoxic nature, inherent stability, and exceptional optical and electrical sensitivity, 2D lead-free double perovskites have attracted considerable research attention. In this work, we present the fabrication of Au-Au/Ag yolk-shell plasmonic nanomaterial-decorated 2D Cs 2 AgBiBr 6 based biosensors for sensitive and selective detection of the cardiac biomarker cardiac troponin I (cTnI). The Cs 2 AgBiBr 6 -based biosensor showed outstanding sensing capabilities, achieving a detection limit of 10 pg/mL, which is considerably below the typical concentration of cTnI in the human blood, highlighting the potential utility of plasmonic nanomaterials and Cs 2 AgBiBr 6 in highly sensitive sensing applications.

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