摘要
A catalytic protocol for "CF "-radical type addition to terminal and β-substituted olefins with Togni's reagent to deliver various α-trifluoromethylated ketones of biomedicinal interests was examined by a series of oxovanadium species under oxygen atmosphere at ambient temperature. Among six different V(O)X bearing (bi)pyridine, imidazole, and (bis)oxazoline ligands and five different oxidovanadium complexes derived from N-salicylidene tert-leucinate, and salen ligands examined, the complexes with 3,5-dibromo substituents and VO(OTf) with bisoxazoline type ligands led to the best results.