Unusual Radiographic Manifestation of Organizing Pneumonia in a Patient with Sjogren’s Syndrome

Sjogren’s syndrome is an autoimmune disease that can affect exocrine organs and many different parts of the body, including the lungs. The usual pulmonary manifestations of Sjogren’s syndrome include bronchiolitis, bronchiectasis and interstitial pneumonias. In Sjogren’s syndrome-associated interstitial pneumonias, the common patterns are nonspecific interstitial pneumonia, lymphocytic interstitial pneumonia, and organizing pneumonia. Here, we report a case of Sjogren’s syndrome with organizing pneumonia. The radiographic presentation of this case was multiple nodules rather than the typical pattern of organizing pneumonia, which usually presents pleura-based consolidation. The diagnosis of organizing pneumonia in this case was made by video-assisted thoracoscopic biopsy. Particular issues regarding radiographic features and diagnostic approach in this case were addressed in this report.