Abstract
A circulating tumor cell capture device includes a chip system and a pump. The chip system includes a confluence chip and a lower chip set. The lower chip set is disposed at a lower surface of the confluence chip, and includes a channel chip, a split chip and a porous membrane. The channel chip is disposed at the lower surface of the confluence chip. The split chip is detachably stacked below the channel chip. The porous membrane is embedded in the channel chip. The specimen passes through the porous membrane and flow between the channel chip and the split chip to make the circulating tumor cell be captured by the porous membrane.