Abstract
A portable optical tomography design for performing elastographic deformation mapping of tissues comprises a coherence light source providing one light beam; a scanning microscope comprising a waveguide having two terminals, a coupler disposed on one terminal, an actuating member connected to the waveguide or the coupler, a first optical reflection member, a beam splitter, and a Fourier-domain spectrometer. The waveguide is actuated by the actuator to traverse a horizontal and vertical motion to prescribe a two-dimensional plane for scanning the tissue sample. Optical fiber is used to connect above elements therebetween. The Fourier-domain spectrometer is coupled with the beam splitter and comprises a second reflection member and an interferogram capturing member. An interferogram produced from the Fourier-domain spectrometer is carried over to a digital signal processor and subsequently an optical coherence tomography image device to generate a three-dimensional image for the scanned tissue.