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Ultra-Nanocrystalline Diamond as a Biomaterial for Enhancing Proliferation and Differentiation of Neural Stem Cells
Patent

Ultra-Nanocrystalline Diamond as a Biomaterial for Enhancing Proliferation and Differentiation of Neural Stem Cells

National Health Research Institutes, National Tsing Hua University, 邱英明, 陳盈潔, 李東慶 and 戴念華
07/04/2011

Abstract

Compositions for promoting growth and/or differentiation of a stem cell are disclosed. The composition comprises: a) a diamond film; b) a stem cell cultured on the diamond film; and c) a medium bathing the stem cell. The stem cell may be a mammalian neural stem cell and the diamond film may comprise a hydrogen-terminated or an oxygen-terminated surface. The hydrogen-terminated surface promotes proliferation and differentiation of a neural stem cell into neurons, and the oxygen-terminated surface promotes a neural stem cell to proliferate and differentiate into oligodendrocytes.

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