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泛用型桿狀病毒表面呈現系統及其應用於次單位疫苗之製備
Patent

泛用型桿狀病毒表面呈現系統及其應用於次單位疫苗之製備

國立屏東科技大學, 林岳宏, 胡育誠 and 劉宏仁
16/02/2010

Abstract

A universal baculovirus surface display system (UBSDS). The signal sequence (SS), transmembrane domain (TM), cytoplasmic domain (CTD) derived from the gp64 protein of baculovirus and histidine-tagged respectively was inserted into the pBacSC vector of UBSDS. Wherein, Four restriction sites between the histidine-tagged and gp64 transmembrane domain were established for expression of different foreign proteins. The UBSDS will therefore be a good platform for developing various subunit vaccines against viruses in the future.

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