摘要
本發明提供一種用以增強癌症免疫治療的口服疫苗，包括β-葡聚醣與mRNA的複合體以及脂質奈米微粒，其中mRNA包括腫瘤抗原的編碼區，脂質奈米微粒包裹β-葡聚醣與mRNA的複合體。
The invention provides an oral vaccine for enhancing cancer immunotherapy, which includes a complex of β-glucan and mRNA and lipid nanoparticles, wherein the mRNA includes the coding region of a tumor antigen, and the lipid nanoparticles wrap the complex of β-glucan and mRNA.