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用於A型流感快篩之自驅動微流體晶片

用於A型流感快篩之自驅動微流體晶片

國立清華大學, Gwo-Bin Lee, Hsi-Pin Ma, 馬郁東, 黃柏鈞, 黎光憲, 陳奕宏 李泳懋
本發明揭露一種用於A型流感快篩之自驅動微流體晶片,該晶片包含:一基板、一疏水層、一親水薄膜層、以及一流道結構層依序積層,該流道結構層的結構包含複數個流道、設置於該複數個流道中的複數個閥門、複數個反應槽、以及複數個開孔,該親水薄膜層係具有對應該流道結構層之該結構的一圖案,且在對應該複數個閥門的位置形成一中斷區域,以使該複數個閥門為疏水性,該流道結構層係由一彈性材料形成,且該複數個閥門在該流道結構層的厚度方向上的高度係高於該複數個流道的高度,以藉由按壓該複數個閥門控制液體流動。 The present invention provides a self-driven microfluidic chip for rapid influenza A detection, said chip comprises: a substrate, a hydrophobic layer, a hydrophilic film layer, and a channel structure layer laminated sequentially, the structure of the channel structure layer includes a plurality of channels, a plurality of valves and reaction tanks in the channels, and a plurality of openings, wherein the hydrophilic film layer includes a pattern corresponding to the structure of the channel structure layer, and forms a disconnected area corresponding to the location of the valves to remain the valves hydrophobic, the channel structure layer is formed of a flexible material, and a height of the valves being higher than the channels in a thickness direction of the channel structure layer, to control liquid flow by pressing the valves.
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