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用於核酸遞送之包含聚乙烯亞胺及聚乙二醇的單一單體衍生之類線狀共聚物
Patent

用於核酸遞送之包含聚乙烯亞胺及聚乙二醇的單一單體衍生之類線狀共聚物

財團法人國家衛生研究院, 胡宇光, 楊重熙 and 林淑宜
16/09/2012

Abstract

A method of synthesizing a random copolymer of polyethyleneimine and polyethylene glycol, comprising exposing ethanolamine in a solution to electromagnetic radiation for a sufficient time to polymerize the ethanolamine (OHCH2CH2NH2) and thereby resulting in formation of the randome copolymer comprising polyethyleneimine and poly (ethylene glycol), wherein the polyethyleneimine comprises ethyleneimine (-CH2CH2NH-) unit and the polyethylene glycol comprises ethylene glycol (-CH2CH2O-) unit, and the polyethylenimine of the random copolymer has a substantially linear backbone.

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