Highly Selective Novel Heme Oxygenase-1 Hits Found by DNA-Encoded Library Machine Learning beyond the DEL Chemical Space

報告

開放取用(OA)

同儕審查

Shuai Han, Xinyun Guo, Min Wang, Huan Liu, Yidan Song, Yunyun He, Kuang-Lung Hsueh, Weiren Cui, Wenji Su, Letian Kuai, …

ACS medicinal chemistry letters, 卷.15(9), 頁碼.1456-1466

12/09/2024

PMID: 39291011

摘要

DNA-encoded library

Heme oxygenase-1 hits

Novel scaffold

Selectivity

Machine Learning

pdf

z- 附件3-han-et-al-2024-highly-selective-novel-heme-oxygenase-1-hits-found-by-dna-encoded-library-machine-learning-beyond-the (1)3.97 MB下載檢視

開放存取(OA)

url

https://doi.org/10.1021/acsmedchemlett.4c00121檢視

已出版(紀錄版本)

1 檢視次數

題名: Highly Selective Novel Heme Oxygenase-1 Hits Found by DNA-Encoded Library Machine Learning beyond the DEL Chemical Space
創作者：: Shuai Han (作者) - WuXi AppTec (China)
Xinyun Guo (作者) - WuXi AppTec (China)
Min Wang (作者) - WuXi AppTec (China)
Huan Liu (作者) - WuXi AppTec (China)
Yidan Song (作者) - WuXi AppTec (China)
Yunyun He (作者) - WuXi AppTec (China)
Kuang-Lung Hsueh (作者) - 國立清華大學, 藥品與醫材法規科學碩士在職學位學程
Weiren Cui (作者) - WuXi AppTec (China)
Wenji Su (作者) - WuXi AppTec (China)
Letian Kuai (作者) - WuXi AppTec (United States)
Jason Deng (作者) - WuXi AppTec (United States)
總頁數: 11
學術資源類型: 報告
出版日期: 12/09/2024
出版資訊: ACS medicinal chemistry letters, 卷.15(9), 頁碼.1456-1466
語言: 英語